From Eonline's Watch With Kristin:
"From donutgirl: You never talk Bartlet Administration. What do you hear?
Aside from Rob Lowe coming back, I hear we get a glimpse into C.J.'s future in episode 21 (the second to last episode). She's meeting with a powerful tech company owner who's very interested in her. So, it looks like that's where she may be heading.